Antibodies

Antibodies

Antibodies

Antibodies are:

  • Globular glycoproteins.
  • Belong to plasma protein group called immunoglobulins.
  • Basic molecule has: 2 long and 2 short polypeptide chains with a dilsulphide bridge holding them together.
  • Each molecule has at least two identical antigen binding sites in its variable region.
  • Flexible hinge allows antibody to bind to antigen.

They work by:

  • Punching holes in bacteria cell wall (effecting osmosis) and make them burst.
  • Attaching to flagella so bacteria are less active.
  • Cause bacteria to clump together so less chance of spreading.
  • Combine with toxins to make them harmless.
  • Coat pathogen so phagocytes are attracted and ingest them.
  • Combine with viruses and bacterial toxins to prevent them entering a cell.
Immunity

Allergies

Allergies

Immunity

Antibody classes

Antibody classes

Immunity

B lymphocytes

B lymphocytes

Immunity

Immune system

Immune system

Immunity

Phagocytosis

Phagocytosis

Immunity

Problems with vaccines

Problems with vaccines